The HIST1H2BK Antibody; Biotin conjugated from MyBioSource.com is a Rabbit Polyclonal antibody to H2B clustered histone 12, and H2BC12. This antibody recognizes Human antigen. The HIST1H2BK Antibody; Biotin conjugated has been validated for the following applications: EIA, Immunoassay, and ELISA.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling